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A study revealed that metformin treatment induced temporal alterations in the expression of specific genes ( BCL2L11 , CDH1 , and CDKN1A ) and proteins in EC cell lines, demonstrating its anti-tumor and anti-proliferative properties in individuals with EC and PCOS (Lange et al., 2021)

Thus, the FPI model can be seen as a viable TBI model for investigating the symptoms linked to TBI
[DOI] [PubMed] [Google Scholar] Moore K.P., Taylor G.W., Gove C., Wood J., Tan K.L., Eason J., William R
Assessment: body weight, body composition, insulin sensitivity, lipid profile, physical activity, bone density, ophthalmologic parameters, cognition
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