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Oppenheimer-Shaanan, Y., Wexselblatt, E., Katzhendler, J., Yavin, E

Ironsulfur cluster protein CDGSH iron sulfur domain (CISD) 1, a mitochondrial outer membrane protein, regulates VDAC in a redox-dependent manner in cells and closes mitochondrial pores to prevent iron accumulation in the mitochondria [49]

doi: 10.1016/j.freeradbiomed.2017.10.345

Juvenile hemochromatosis is an autosomal recessive disorder which manifests usually under the age of 30 years with significant iron overload

The diverse and dynamic phenotypes of reactive astrocyte reflect their context-dependent heterogeneity and adaptive capacity, which enables structural, molecular and functional adaptations to shifting physiological conditions and pathological insults

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