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The intense lipid oxidation disrupts ion balance within the cell, leading to reduced membrane flexibility, increased permeability and the formation of protein-based pores
Grote A, Caffrey CR, Rebello KM, Smith D, Dalton JP, Lustigman S

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Downregulation of EAAT2 also contributes to the pathogenesis of neurodegenerative diseases, epilepsy, migraine and depression, as described in the previous sections

(2017) 12:e0170547

[DOI] [PMC free article] [PubMed] [Google Scholar] 104.De Flora S., Balansky R., La Maestra S
