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Because of the disappointing results of clinical trials, minimizing homocysteine levels is no longer the primary goal of our recommendations

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Head E, Garzon-Rodriguez W, Johnson JK, Lott IT, Cotman CW, Glabe C (2001) Oxidation of Abeta and plaque biogenesis in Alzheimers disease and Down syndrome
Other pro-inflammatory cytokines have also been linked to dopaminergic signaling

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