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Challenges with combining molecularly target agents, Clinical Trial Design: Part 2: Clinical Trials Issues with Molecularly Targeted Agents, US

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Gynecomastia, characterized by breast enlargement, occurs in 44% of cirrhosis cases, also due to elevated estrogen levels, and is related to conditions like extreme obesity, hypogonadism, and various adrenal and testicular diseases (88, 89)

A careful examination, however, revealed a background of faint erythema often with small scales along with the darkened skin