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Crystal Structure and Functional Characterization of Selenocysteine-Containing Glutathione Peroxidase 4 Suggests an Alternative Mechanism of Peroxide Reduction

Finally, not all standards for all putatively identified metabolites were commercially available, such that the targeted quantitative analysis of some MDMs was not possible, thus reducing the sensitivity of the targeted vs the untargeted test
Several urinary metabolites derived from cytochrome P450 2E1 mediated bioactivation of furan to the highly reactive intermediate cis -2-butene-1,4-dial (BDA) and subsequent reaction of BDA with cellular nucleophiles such as free or protein-bound lysine and cysteine residues and glutathione (GSH) have been suggested as potential biomarkers of furan exposure (Kellert et al

PubMed CrossRef Duailibi MS, Cordeiro Q, Brietzke E, et al
So why is glutathione dubbed the master antioxidant
