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Earlier studies demonstrated the interaction of genetic variants and environmental factors that contribute to the escalating situation of metabolic syndrome [21-24]

ZhaoLYangLZhangJXiaoYWuMMaTet al Bmal1 promotes prostaglandin E 2 synthesis by upregulating Ptgs2 transcription in response to increasing estradiol levels in day 4 pregnant mice
demonstrated that treatment with the probiotic microbes L

doi: 10.18632/aging.100681
Given the significant stiffness of the TME, anti-fibrosis emerges as a promising therapeutic approach for augmenting immunotherapy by targeting remodeled ECM components
For example, leukemia linked to chronic benzene exposure may develop within a few years, whereas cancers caused by asbestos or arsenic often take several decades to manifest, even after exposure has ceased [246]
