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Fluorescence was measured at 360/460 excitation/emission on the Synergy H1 spectrophotometer (BioTek) using Skanit for Multiskan GO v.2.0

In RA, rapamycin inhibits proliferation and induces apoptosis of fibroblast-like synoviocytes via the AKT/mTORC1 pathway, reducing joint inflammation and tissue damage

This nanoparticle has demonstrated good antitumor effects both in vitro and in vivo in breast cancer cells (Li et al., 2017)

doi: 10.3892/or.2022.8428 136 VirayHMcDermottDFEinsteinDJ