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Clinically, lichenified eczema can exhibit hyperpigmentation and mimic the velvety texture of acanthosis nigricans via accentuation of skin markings due to chronic rubbing or irritation [7]
The antibiotic usage reducing the SCFAs producing bacteria such as Faecalibacterium prausnitzii , and Roseburia destroys the mucus layer and disrupts tight junctions of the intestinal barrier, making the gut prone to infections (Zhang, Cheng, et al
116,605,606 Similarly, astrocytic reactivity seems to fade at the advanced stages of AD in human patients
To improve prognosis, in a patient with peripheral arterial atherosclerosis active pharmacological and non-pharmacological management should be urgently initiated [10]
J., Hastings T
Strahl & Errington, 2017)
