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Gibbs free barrier and released energies involved in hydrogen abstraction from the different sites of glutathione by an OH radical were studied at the B3LYP/6-31G(d,p), B3LYP/AUG-cc-pVDZ, M06/AUG-cc-pVDZ, M06-2X/AUG-cc-pVDZ levels of density functional theory

Early detection is key, using: Serum ceruloplasmin levels 24-hour urinary copper excretion Liver biopsy or genetic testing If caught early, treatment with chelating agents like penicillamine can prevent long-term damage and give patients a near-normal life

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