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Low JA, Handley-Derry MH, Burke SO, Peters RD, Pater EA, Killen HL, Derrick EJ: Association of intrauterine fetal growth retardation and learning deficits at age 9 to 11 years

The peptide itself was not the problem

Studies by Pickart and colleagues published in 2012-2018 showed that GHK-Cu treatment of cultured human fibroblasts altered expression of several thousand genes, with patterns indicating increased expression of genes involved in tissue repair, antioxidant responses, protein synthesis, and cellular rejuvenation

Unlike many newer peptides, AOD9604 was originally developed and taken through formal pharmaceutical trials before continuing on as a widely used laboratory research compound

This means understanding its precise mechanism, its limitations, and its safety profile

Statistical analysis Statistical analysis was performed using R software ( KaplanMeier survival analysis was performed with greyzoneSurv packages in R for the survival analysis