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[10] [12] High-dose ascorbic acid may diminish the therapeutic effects of certain chemotherapeutic agents, such as bortezomib, due to its antioxidant properties

Because no studies have evaluated potential risks, such as effects on the fetus or pregnancy outcomes, clinicians advise against NAD+ therapy during pregnancy out of an abundance of caution

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Try fasting Eating causes an inflammatory response, while fasting reduces circulating levels of inflammatory mediators, notes Jandes

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A smaller per-injection peak may reduce nausea and heart-rate pressure during escalation, and a smaller trough may soften the late-week hunger some users report