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For example, novel SBP2 truncation mutations result in abnormal thyroid function, delayed bone development, congenital myopathy, and cognitive impairment in human subjects due to deficiencies in selenoproteins, including GPx-1 (121)

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Tesamorelins effects depend on intact pituitary function and normal GH responsiveness, while AOD9604 works directly on adipose tissue regardless of GH status

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Glutamate released by glioma cells in the extracellular milieu caused excitotoxicity to the surrounding neurons by Ca 2+ influx

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