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4.4 Interactions between cartilage and synovium 4.4.1 Interplay between cytokines released by chondrocytes and synovial cells When cartilage is damaged, chondrocytes release proteoglycan fragments, type II collagen fragments, and diverse injury-associated factors that synovial cell surface pattern recognition receptors (PRRs) can detect, prompting synovial hyperplasia and proinflammatory cytokine secretion (139)

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Glutathione an antioxidant that supports a brighter, more radiant-looking complexion

Amlodipine's ability to suppress Fe 2+ entry and effectively quench the free radical formation and oxidative damage makes it an effective agent to improve the effectiveness of chelation therapy

van Haren FMP, Page C, Laffey JG, Artigas A, Camprubi-Rimblas M, Nunes Q, et al

svH1C, a mimetic of sialic acid, binds to sialic acidspecific plant lectins (Eggink et al., 2010)