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As more feasibility data becomes available, these results show favorable reduction in MR severity and improvement in patient symptoms with an acceptable early mortality rate among high surgical risk populations

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The HTML:TML ratio was decreased by IDH1 inhibition and rescued by KG (Extended Data Fig
[DOI] [PubMed] [Google Scholar] Baric I, Zschocke J, Christensen E, Duran M, Goodman SI, Leonard JV, Muller E, Morton DH, Superti-Furga A, Hoffmann GF

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