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In the most apical region of the epithelium there is an intercellular gap (around 90 ) named zonula occludens or tight junctions, followed by the zonula adherens (gap of 200 ), followed by the macula adherens or desmosomes (gap of ~240 ) ( zonula occludens (ZO) family
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The increase in Th2-associated cytokines can perpetuate systemic inflammation and exacerbate hallmark symptoms such as fatigue and musculoskeletal pain [57]
Nov 2023;41(6):844-853
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Micro nutrients as immunomodulators in the ageing population: a focus on inflammation and autoimmunity
