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Carnitine biosynthesis intermediates measurement Measurements of carnitine biosynthesis intermediates, including N-6-trimethyllysine, gamma-butyrobetaine, and HTML/TML ratio, were performed at the Amsterdam UMC laboratory for Genetic Metabolic Diseases in Amsterdam, the Netherlands

L-carnitine is involved in the transport of fatty acids into mitochondria for energy production

After overnight incubation at 35 C, fungal growth in each well was assessed

These results indicate that no proportional relationship can be found between plasma and muscle l-carnitine concentration and that the lowest dose (0.1 g) supplemented for 28 days is already able to induce the maximal muscle concentration