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In oncology, clinical trials show promise with ASOs for malignant glioblastoma and pancreatic cancer, antibodies for metastatic melanoma and renal cell carcinoma, and chemical inhibition for glioblastoma, as well as augmentation of tumour vaccines for non-small-cell lung cancer

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Many other pathways are also involved in these effects, like mTOR and AMPK signaling pathways that increase the capacity of cells to renew, proliferate, and differentiate
