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In this context, the increased extracellular glutamate can bind to its receptor, the metabotropic glutamate receptor 5 (mGluR5) on the stellate cell surface, stimulating it to synthesize 2-arachidonoylglycerol (2-AG) [155], which in turn, once released into the extracellular space, binds to the cannabinoid receptor-1 (CB1R) on hepatocytes, triggering a mechanism of de novo lipogenesis and therefore of fat accumulation [156] (Figure 7)

Sodium PCA restores the Natural Moisturising Factor that cleansing inevitably depletes

Topical cannabinoid receptor 1 agonist attenuates the cutaneous inflammatory responses in oxazolone-induced atopic dermatitis model

[287] GCMS of amphetamine and methamphetamine with the chiral derivatizing agent Mosher's acid chloride allows for the detection of both dextroamphetamine and dextromethamphetamine in urine

In contrast, reduced risk of poor outcome was observed in patients with low tGSH levels in CE group on adjusted model (Table 4)