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Hence, a step-by-step, multimodal approach, which includes a mix of treatments and procedures targeting the melanin synthesis pathways, the anti-inflammatory environment, senescence and vascularity, should be used, along with avoidance of exacerbating factors such as UV light and hormonal contraception (Figure 3)

Moszyska, M

The lysine residues serve as ubiquitination target sites and are clustered in the Neh2 domain between the ETGE and DLG motifs

Foltz W

Menander-Huber, K

SOD activity was measured in a reaction mixture containing 50 mM phosphate buffer (pH 7.8), 0.1 mM EDTA, 13 mM methionine, 75 M nitroblue tetrazolium (NBT), 2 M riboflavin, and 50 l enzyme aliquot 51