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ROS and RNS derived from NO and superoxide may also cause local cellular damage by reacting with proteins, lipids and nucleic acids (Valko et al
2022;8:e174
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Heme is a vital cofactor for ETC Complexes III and IV, and its synthesis depends on ferrochelatase inserting Fe into protoporphyrin IX [34]
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That uneven skin tone is not going away
