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A.MalomouzhA

Despite their selectivity, aptamers may suffer from limited nuclease stability and require chemical modification (e.g., 2-fluoro or 2-O-methyl substitutions) to remain intact in biological fluids [160]

The study, published in Nature , shows that tumors can break down glutathione to support their growth, challenging long-held assumptions about its role in human health

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VH3 BCR, VH3 B Cell Repertoire
However, excess ROS interact with nitric oxide to form peroxynitrite, reducing nitric oxide bioavailability
