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Fiorucci S, Distrutti E
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Retatrutide is an investigational triple hormone agonist (GLP-1, GIP, glucagon) showing promising early results for obesity and type 2 diabetes, while tirzepatide is an FDA-approved dual agonist (GLP-1, GIP) available for use today

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The incidence of adverse reactions, including nausea, vomiting, headache, and mild gastric discomfort, was recorded and compared between the two groups during the treatment period
