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Orally-swallowed B12 tablets are just as effective as injections in the vast majority of patients, except those with digestive issues that may hamper absorption

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Nat Cell Biol 2012

Crucially, this therapeutic benefit was achieved with a favorable safety profile, as QLQX demonstrated tolerability comparable to placebo, with no significant hepatic or renal toxicity and no increase in arrhythmias or other major adverse events