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2019;52:e8567

Supplemental Se may also promote inhibition of cell growth and apoptosis by multiple mechanisms, including the enhanced accumulation of Se-metabolites that could be toxic to cells (75, 303)

Patients may have hip pain, clicking and locking of joint and restricted range of motion

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Discard if discoloration, cloudiness, or precipitate develops

Accumulated H 2 O 2 after UA degradation During the catalytic degradation of UA (1 mM) facilitated by natural uricase (5 U/mL) and PDA@Pt (50 g/mL), 1 mL samples were collected every 10 min