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inhibits lipogenesis (fat synthesis)

Distribution of cystine/glutamate exchange transporter, system xc, in the mouse brain

Reduced CII activity has consequences for central carbon metabolism because CII is involved in the conversion of succinate to fumarate within the TCA cycle 73

232 Nrf2 not only regulates oxidative/xenobiotic stress response but also represses inflammation by opposing transcriptional upregulation of a number of pro-inflammatory cytokine genes

Glasauer and Chandel, 2014)
