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References 1 PizzatoMLiMVignatJLaversanneMSinghDLa VecchiaCet al
Source : Mandal, P

Oxidative stress and regulation of glutathi one in lung inflammation

Glutathione S-conjugates are usually sequestered by distinct ABC transporters from the cytosol into the vacuole for degradation, although breakdown of glutathione, oxidized glutathione and glutathione S-conjugates also happens outside the vacuole 56

All of the N-modified analogues ( 1.65 , 1.70 , and 1.71 ) showed a retention of activity with the GPx and GR enzymes, indicating that antioxidation activities through this pathway is not hindered by modification at the peptide bonds

Cell Mol Life Sci CMLS 63(4):414434 Verma S et al (2021) Implications of oxidative stress in chronic kidney disease: a review on current concepts and therapies
