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On the one hand, they contribute to the survival and proliferation of B cells specific for some environmental foreign antigens, while on the other hand, they are able to suppress the proliferation and differentiation of foreign antigen-nonspecific B cells by creating a proper environment that mainly promotes the development of antigen-specific germinal center B cell clones in peripheral lymphoid organs (175, 178)

[DOI] [PubMed] [Google Scholar] Li Y, Heng J, Sun D, Zhang B, Zhang X, Zheng Y, Shi WW, Wang TY, Li JY, Sun X, et al

PMID: 2153863

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Szabo, another former Selye student, built on those findings to show that cytoprotective compounds work, in part, by protecting the blood vessels just beneath the stomach lining