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Identification of 2-[2-[2-(5-bromo-2- methoxyphenyl)-ethyl]-3-fluorophenyl]-4,5-dihydro-1H-imidazole (ML00253764), a small molecule melanocortin 4 receptor antagonist that effectively reduces tumor-induced weight loss in a mouse model

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The dose is adjusted as needed to get the best results
2021;10 doi: 10.7554/eLife.58591
Natural supplement sources for vitamin B12 include beef liver and brewers yeast