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Design and discovery of flavonoid-based HIV-1 integrase inhibitors targeting both the active site and the interaction with LEDGF/p75

doi: 10.1016/j.ejphar.2017.06.019

Mechanistically, low CFTR expression impairs the expression of the chloride ion-sensitive with-no-lysine kinase 1 (WNK1) protein, thereby leading to activation of transient receptor potential cation vanilloid 4 (TRPV4)

Lai Z, Hanczko R, Bonilla E, et al
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10.1093/gerona/54.11.b492 J

Reduced muscle mass was shown to be related to the onset of complications from COVID-19, and KD represents a viable approach to preserving muscle mass in post-COVID (Schiaffino et al., 2021)
