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The association of Fas with these raft markers in aged RBCs suggests that lipid rafts play a crucial role in initiating and regulating the extrinsic death pathway in erythrocytes

Single myocyte studies have also shown that cell-wide m depolarization, through a reactive oxygen species (ROS) -induced ROS release mechanism, can be triggered by global depletion of the antioxidant pool with diamide, a glutathione oxidant

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