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Positive results were also obtained in the treatment of vitiligo with GliSODin superoxide dismutase drugs

Based on site-directed mutagenesis and biochemical detection, three amino acid residues (LYS50, LEU53 and TYR89) were identified to be important for LYN-1604 binding and activation of ULK1

Beyond systemic symptoms, vitamin B12 deficiency is also associated with a range of oral manifestations, including burning mouth syndrome, recurrent aphthous ulcers, mucosal inflammation, and trigeminal nerve-related pain, which are often underdiagnosed or misattributed to other conditions (Bao et al., 2021

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