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J Clin Endocrinol Metab 80(1):160164

Global Incidence and Prevalence of Idiopathic Pulmonary Fibrosis

IGF-LR3 is an 83 amino acid analog of human IGF-1, actually comprising the complete human IGF-1 sequence substituting arginine for glutamine at position 3, and it has a 13 amino acid extension at the N-terminus

doi: 10.1126/sciimmunol.abd2071 148

The positive effect of the present disclosure is that a pyrimidine carboxamide compound is provided, which can be used as an inhibitor of Vanin enzyme, especially an inhibitor of Vanin-1