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It promotes tissue repair throughout the body from the gut lining to tendons and ligaments by stimulating new blood vessel formation and modulating inflammatory pathways

The majority of IGF-1 is made by the liver and is transported to other tissues in the bloodstream, where it acts as an endocrine hormone [3]

Cumulative apoptotic/live cell burden over time was determined by calculating the area under the curve for each mouse (bottom)

Early administration of lactate in rat organotypic hippocampal slices after oxygen-glucose deprivation protected against neuronal death, decreased lesion size and showed better neurologic outcomes in a mouse model of middle cerebral artery occlusion (Berthet et al., 2011), in mouse cortical neuron cultures (Jourdain et al., 2016) and in rat cortex in vivo (Ros et al., 2001)

Cancer Sci (2022) 113:376675

Dysregulated immune responses in SARS-CoV-2-infected patients: a comprehensive overview