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Preclinical and clinical studies demonstrate that selective NR2B receptor antagonists and non-selective, low trapping NMDA receptor antagonists, as well as allosteric modulators of NMDA channels such as GLYX-13 produce antidepressant responses in rodent models and in humans, supporting this possibility 52,55,160,168,169

[CrossRef] [Google Scholar] Postanalytical tools improve performance of newborn screening by tandem mass spectrometry

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Certain medical issues may pose some additional risk factors