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doi: 10.1038/emboj.2011.105

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Translation of the findings from MASLD/MASH animal models to humans Animal models are crucial for better understanding human MASLD pathogenesis, identifying possible therapeutic targets and disease biomarkers, as well as testing novel drugs

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PloS One 2016, 11 (9), e0162198

Additionally, multiple immune-related pathways were activated via lipid peroxidation, such as TLR4, AGER and STING1 pathways (Fig