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In the last years, several non-histone proteins have been identified as targets of Kla [15], revealing a crucial multifaceted role of this PTM in cancer biology

10.1073/pnas.0900206106 25 MaughanS

Rare associations with vaccination or surgery have been reported, although causal links remain controversial (12)

IKK is overexpressed in tumors, including pancreatic, breast, ovarian, lung, myeloma, rectal, and leukemia cancers, and IKK-mediated NF-B pathway is a key signal transduction pathway involved in the occurrence and development of tumors [39]

(1) N Pandya, R DeMott-Friberg, C Y