oral glutathione bioavailability randomized controlled trial liposomal study A Targeted Metabolomic Assessment of Oral Glutathione Bioavailability and Safety in Liposomal glutathione outperforms plain glutathione
Description
Although such DHA uptake and reduction can at least transiently generate a trans-plasma membrane gradient of ascorbate [16], several lines of evidence suggest that it is not the major route

Sources Lachner, C., Steinle, N

Cell 188 , 11371155 (2024)

The SpectraCell Micronutrient Test is the most advanced cellular-level nutrient test available

brucei only 1-C-Grx1, but not 1-C-Grx2 and 3, is capable of partially rescuing the deleterious phenotype of the Grx5 yeast mutant [188]

This means you could be taking large doses and still getting very little benefit
