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The overall SPRINT trial showed intensive BP lowering to target of less than 120 mm Hg systolic, versus a target of less than 140 mm Hg, was associated with a 25% reduction in fatal and nonfatal major cardiovascular events and death from any cause (694)

The presence of delusions and auditory hallucinations indicates severe impairment, automatically qualifying the episode as manic rather than hypomanic

They also considered the benefits of using HCG alongside TRT