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FcR-mediated functions control a broad array of antibody-driven therapeutic mechanisms, including complement-dependent cytotoxicity (CDC), antibody-dependent cell cytotoxicity (ADCC), antibody-dependent cell phagocytosis (ADCP), and the induction of cell death by apoptosis

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30 ) by the central laboratory at screening

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Certain lifestyle factors such as smoking cigarettes, or drinking alcohol can be a trigger