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They are well-known for their role in activating transcription of genes involved in gluconeogenesis and FAO (89)

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El diagnstico intrauterino de la hemorragia suprarrenal es poco frecuente, con evolucin del hematoma conforme avanza el tiempo y es 3 a 4 veces ms frecuente en la glndula suprarrenal derecha

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Clinical trials using combinations of CoQ10 with cross-linked hyaluronic acid (XL-HA) have shown enhanced treatment outcomes in DED patients, attributed to CoQ10s antioxidant effects and HAs inherent water retention and viscoelasticity properties, which are essential for repairing ocular tissues (Postorino et al., 2018

Moreover, mitochondrial dysfunction and related oxidative stress can activate the innate branch of the immune system, leading to the release of pro-inflammatory cytokines influencing various depression-related pathophysiological mechanisms: monoaminergic neurotransmission disruption, tryptophan degradation toward neurotoxic catabolites, glutamate-related excitotoxicity, decreased neurotrophic factors and alterations in the hypothalamic-pituitary-adrenal axis [3, 33, 59]