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Higher rates of toxicity were reported in patients receiving ramucirumab treatment ( Tyrosine Kinase Inhibitors Tyrosine kinase inhibitors (TKIs) are small molecules that inhibit the kinase domain of RTKs thus inhibiting receptor activation and downstream signaling ( Sorafenib Sorafenib (Nexavar ) is an oral multikinase inhibitor of VEGFR, PDGF receptor (PDGFR), and Raf (Pitoia and Jerkovich, 2016)

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BPC-157 is a research peptide not approved by Health Canada for human therapeutic use

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At present, anti-angiogenic drugs have obtained positive results in the treatment of GC, but the discovered response biomarkers have not been verified as predictive or prognostic

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