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28 days) improves cognitive function in the cognitive impairment model of aged rats, enhances synaptic plasticity in the hippocampus, and increases the expression of brain-derived neurotrophic factor (BDNF) [3]

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Thus, while transcriptional changes mediated by NHR-49 correspond with the maintenance of energy homeostasis during fasting, animals possessed the capacity to restore their ATP levels upon nutrient replenishment

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The term discordance refers to situations where LDL-C and LDL-P levels diverge from each other