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By improving the heart's metabolic efficiency, L-Carnitine Fumarate enhances cardiac output and stroke volume, allowing the heart to pump blood more effectively without having to beat as rapidly

CI Confidence interval RR Risk ratio MD Mean difference RCT Randomized controlled trial GRADE Working Group grades of evidence High certainty: We are very confident that the true effect lies close to that of the estimate of the effect

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Our study showed that L-carnitine reverses the TNF--induced muscle cell atrophy caused by regulation of the Akt/P70S6K/FOXO3a pathways, and by inhibiting muscle-specific ubiquitin ligases