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One study suggests that the cholesterol-to-bile acid ratio is vital to supporting the homeostatic redox environment of HSCs [240]
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Therefore, it is plausible that thyroid hormones can upregulate HO-1 expression via ROS signaling
Nrf2 is expressed the majority of cell types, where it is anchored in the cytosol by an inhibitory protein, Kelch-like ECH-associated protein (Keap1)
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