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Lin et al.5 reported ring-like pattern and its variant (fish scale-like pattern and hyphal pattern) in 20 labial and 4 penile lesions of mucosal melanotic macules

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Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation

The tissue is excised with a scalpel or punch
doi:10.1016/j.peptides.2005.01.029