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Initiation of LDL apheresis should generally be delayed until approximately 5 years of age, except when evidence of atherosclerotic vascular disease is present

One of the enzymes in this pathway, -butyrobetaine hydroxylase, is absent from cardiac and skeletal muscle but highly expressed in human liver, testes, and kidney [4]

doi: 10.1128/JVI.77.10.5855-5862.2003

LPS-induced pneumonitis generally requires anti-infective therapy, whereas RP may also warrant antibiotic treatment if complicated by an infection

Collectively, these effects could increase the enterocytic secretion of apoB-48-containing chylomicrons