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Days to weeks to replenish the depleted vesicular monoamine transporters (VMATs), monoamine oxidase (MAO), as well as catechol-O-methyltransferase (COMT), metabolize unprotected neurotransmitters, given the post-synaptic cell are consequently never excited [154,155]

In the case of an acute inflammatory condition the effect of the cortisone will therefore mostly be seen after about 2 days

After reconstitution with bacteriostatic water, refrigerate at 2-8C and use within 14-21 days

Shorten the cycle if: results have plateaued for 2+ weeks despite dose optimization, you are experiencing fatigue or other signs of potential receptor desensitization, or your goals have been achieved before the planned cycle end

doi: 10.1016/j.actbio.2017.12.043 Zhang, C., Xie, Y., Chen, H., Lv, L., Yao, J., Zhang, M., et al

For UK clinics selling it as a treatment, the MHRA position now creates direct legal exposure [1]