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[96] detected elevated levels of pro-inflammatory cytokines (IL-1, IL-6) and oxidative stress markers (nitrotyrosine, 4-hydroxynonenal) in the cortical and hippocampal regions of a mouse model of ME/CFS

ALC has contributed to enhanced learning capacity and cognitive function in rats by providing acetyl groups for acetylcholine synthesis, thereby exerting an effect in cholinergic neurotransmission ( 4.1 Limitations Small animal models provide advantages in the study of TBI in the ability to screen for pathology that is otherwise hard to determine

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A pivotal 2009 study published in Neuro Endocrinology Letters by Maes et al

Nat Commun 13 , 970 (2022)