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In the coming years, it will be revealing for researchers to build on lab-based evidence in well-designed, large-scale clinical trials

The NLRP3 inflammasome exerts indirect regulation of pyroptosis via the caspase-1, reactive oxygen species (ROS), and Panx1 signaling pathways ( 2.1.2.3 Pro-inflammatory cytokines Pro-inflammatory cytokines such as IL-1 and IL-18 can affect renal endothelial cells, leading to alterations in microcirculation and ultimately resulting in SA-AKI

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Liu J, Kuang F, Kroemer G, Klionsky DJ, Kang R, Tang D

Choline: Essential for liver health, choline facilitates the transport of fat out of the liver via VLDL (very low-density lipoprotein) particles

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